The EBI3 Polyclonal Antibody (CAB19613) is a valuable tool for researchers studying EBI3, a protein that plays a crucial role in the immune system. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications. By binding to the EBI3 protein, this antibody enables researchers to detect and analyze EBI3 in various cell types, making it ideal for studies in immunology and cancer research.
EBI3 is a subunit of interleukin-27, a cytokine that is involved in regulating immune responses. By understanding the role of EBI3 in the immune system, researchers can gain insights into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. This antibody provides a valuable tool for investigating the function of EBI3 and developing potential therapies that target this protein for therapeutic purposes.
Product Name:
EBI3 Rabbit Monoclonal Antibody
SKU:
CAB19613
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 130-229 of human EBI3 (Q14213).
endoplasmic reticulum lumen, external side of plasma membrane, extracellular region, extracellular space, plasma membrane
Calculated MW:
25kDa
Observed MW:
31kDa
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
Purification Method:
Affinity purification
Gene ID:
10148
Clone Number:
ARC2190
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using EBI3 Rabbit mAb (CAB19613) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
