The EB3/ MAPRE3 Polyclonal Antibody (CAB19768) is a valuable tool for researchers studying the EB3 protein, a microtubule plus-end binding protein that plays a crucial role in microtubule dynamics and cell division. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.EB3, also known as MAPRE3, is essential for regulating microtubule dynamics during cell division and cell migration. Its aberrant expression has been implicated in various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities. The EB3/ MAPRE3 Polyclonal Antibody allows for the detection and analysis of EB3 protein levels in different cell types, making it a valuable tool for researchers in cell biology, cancer research, and neurobiology.
By understanding the functions of EB3 and its role in disease processes, researchers can gain insights into potential therapeutic targets for treating conditions associated with dysregulated microtubule dynamics. The EB3/ MAPRE3 Polyclonal Antibody offers a reliable means to investigate the expression and localization of EB3 protein in diverse experimental settings, facilitating further advances in understanding the molecular mechanisms underlying disease development.
Product Name:
EB3/MAPRE3 Rabbit Monoclonal Antibody
SKU:
CAB19768
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 182-281 of human EB3/MAPRE3 (Q9UPY8).
Cytoplasm, Microtubule Cytoskeleton, Microtubule organizing center, Perinuclear region of cytoplasm, Spindle midzone
Calculated MW:
32kDa
Observed MW:
32kDa
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.
Purification Method:
Affinity purification
Gene ID:
22924
Clone Number:
ARC2305
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using EB3/MAPRE3 Rabbit mAb (CAB19768) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
