The Anti-EAAT1 (SLC1A3) Antibody (CAB9712) is a valuable tool for researchers studying the EAAT1 protein, also known as SLC1A3, which plays a key role in glutamate transport in the brain. This polyclonal antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.EAAT1 is a crucial protein involved in the regulation of glutamate levels in the central nervous system, and dysregulation of EAAT1 has been linked to various neurological disorders such as epilepsy, Alzheimer's disease, and amyotrophic lateral sclerosis (ALS).
By targeting EAAT1 with this antibody, researchers can investigate the function and expression of this important transporter protein in different cell types, providing insights into its role in neurological diseases and potential therapeutic interventions.With its high specificity and validated performance, the Anti-EAAT1 (SLC1A3) Antibody (CAB9712) is a valuable tool for studies in neuroscience, neurodegenerative diseases, and drug discovery targeting glutamate homeostasis.
Product Name:
EAAT1/SLC1A3 Rabbit Monoclonal Antibody
SKU:
CAB9712
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human EAAT1/SLC1A3 (P43003).
This gene encodes a member of a member of a high affinity glutamate transporter family. This gene functions in the termination of excitatory neurotransmission in central nervous system. Mutations are associated with episodic ataxia, Type 6. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6507
Clone Number:
ARC1714
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates from Mouse brain using EAAT1/SLC1A3 Rabbit mAb (CAB9712) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
