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Dynein intermediate chain 1 Rabbit Monoclonal Antibody (CAB3624)

SKU:
CAB3624
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CILD1
DIC1
ICS1
PCD
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Dynein intermediate chain 1 Rabbit Monoclonal Antibody
SKU:CAB3624
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Dynein intermediate chain 1 (Q9UI46).
Sequence:MIPA SAKA PHKQ PHKQ SISI GRGT RKRD EDSG TEVG EGTD EWAQ SKAT VRPP DQLE LTDA ELKE EFTR ILTA NNPH APQN IVRY SFKE GTYK PIGF VNQL AVHY TQVG NLIP KDSD EGRR QHYR DELV AGSQ ESVK VISE TGNL EEDE EPKE LETE PGSQ TDVP AAGA AEKV TEEE LMTP KQPK ERKL TNQF NFSE RASQ
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:PCD; DIC1; ICS1; CILD1; Dynein intermediate chain 1
Positive Sample:Mouse lung,Mouse testis,Rat testis
Conjugate:Unconjugated
Cellular Localization:9+2 motile cilium, Centrosome, Ccilium, Cytoskeleton, Dynein axonemal particle, Extracellular region
Calculated MW:79kDa
Observed MW:79kDa

This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:27019
Clone Number:ARC2061
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Dynein intermediate chain 1 antibody (CAB3624) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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