Dynein intermediate chain 1 Rabbit Monoclonal Antibody (CAB3624)
- SKU:
- CAB3624
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CILD1
- DIC1
- ICS1
- PCD
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Dynein intermediate chain 1 Rabbit Monoclonal Antibody |
SKU: | CAB3624 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Dynein intermediate chain 1 (Q9UI46). |
Sequence: | MIPA SAKA PHKQ PHKQ SISI GRGT RKRD EDSG TEVG EGTD EWAQ SKAT VRPP DQLE LTDA ELKE EFTR ILTA NNPH APQN IVRY SFKE GTYK PIGF VNQL AVHY TQVG NLIP KDSD EGRR QHYR DELV AGSQ ESVK VISE TGNL EEDE EPKE LETE PGSQ TDVP AAGA AEKV TEEE LMTP KQPK ERKL TNQF NFSE RASQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PCD; DIC1; ICS1; CILD1; Dynein intermediate chain 1 |
Positive Sample: | Mouse lung,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | 9+2 motile cilium, Centrosome, Ccilium, Cytoskeleton, Dynein axonemal particle, Extracellular region |
Calculated MW: | 79kDa |
Observed MW: | 79kDa |
This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 27019 |
Clone Number: | ARC2061 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |