The DTX1 Polyclonal Antibody (CAB20499) is a valuable tool for researchers studying the DTX1 protein, a key regulator of Notch signaling pathway. This antibody is raised in rabbits and has been validated for use in a variety of applications, including Western blot analysis.DTX1, also known as deltex E3 ubiquitin ligase 1, plays a crucial role in regulating the Notch signaling pathway, which is involved in various cellular processes like cell differentiation, proliferation, and apoptosis. Dysregulation of the Notch pathway has been implicated in various diseases, including cancer and developmental disorders.
By using the DTX1 Polyclonal Antibody, researchers can detect and analyze the expression of DTX1 protein in different cell types, providing valuable insights into its function and potential therapeutic implications. This antibody is suitable for studies in oncology, developmental biology, and molecular biology, shedding light on the role of DTX1 in health and disease.
Product Name:
DTX1 Rabbit Polyclonal Antibody
SKU:
CAB20499
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human DTX1 (NP_004407.2).
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
Purification Method:
Affinity purification
Gene ID:
1840
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Daudi cells using DTX1 Rabbit pAb(CAB20499) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
