The Anti-DPP3 Polyclonal Antibody (CAB9351) is specifically designed for research involving DPP3, a cell surface protease implicated in various biological processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DPP3 protein, researchers can effectively detect and analyze DPP3 expression in different cell types, making it well-suited for studies in immunology, cancer research, and other fields.DPP3, also known as dipeptidyl peptidase-3, plays a critical role in modulating peptide degradation and signal transduction pathways.
Its involvement in these processes makes it a key target for investigation in diseases such as cancer, cardiovascular disorders, and metabolic conditions. Understanding the function of DPP3 is essential for the development of therapeutic strategies that target this protease in various pathological contexts.Overall, the Anti-DPP3 Polyclonal Antibody (CAB9351) offers researchers a reliable tool for studying DPP3 expression and function, providing valuable insights into its role in biological mechanisms and potential therapeutic applications.
Product Name:
DPP3 Monoclonal Antibody
SKU:
CAB9351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 638-737 of human DPP3 (Q9NY33).
HT-29,HCT116,A-431,Rat testis,Rat brain,Rat liver,Mouse large intestine,Mouse heart
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
83kDa
Observed MW:
70kDa
This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10072
Clone Number:
ARC2778
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using DPP3 Rabbit mAb (CAB9351) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
