The DNAJC17 Polyclonal Antibody (CAB20168) is a valuable tool for researchers studying DNAJC17, a member of the heat shock protein family involved in protein folding and quality control in the endoplasmic reticulum. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By specifically binding to the DNAJC17 protein, researchers can accurately detect and analyze this essential molecular chaperone in various cell types.DNAJC17 plays a crucial role in maintaining protein homeostasis and ensuring proper protein folding under stress conditions. Its function in the endoplasmic reticulum makes it a key player in cellular protection against proteotoxic stress and misfolded protein aggregation.
Research on DNAJC17 is essential for understanding its involvement in diseases such as neurodegenerative disorders, cancer, and metabolic conditions, where protein quality control mechanisms are compromised.By utilizing the DNAJC17 Polyclonal Antibody (CAB20168), scientists can advance their studies on protein folding mechanisms, cellular stress response, and disease pathogenesis. This antibody is a valuable tool for investigating the functional significance of DNAJC17 and its potential as a therapeutic target in various pathological conditions.
Product Name:
DNAJC17 Rabbit Polyclonal Antibody
SKU:
CAB20168
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human DNAJC17 (NP_060633.1).
Predicted to enable RNA binding activity. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and toxin transport. Predicted to be located in cytoplasm and nucleus.
Purification Method:
Affinity purification
Gene ID:
55192
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DNAJC17 Rabbit pAb (CAB20168) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
