DNA Polymerase gamma Rabbit Monoclonal Antibody (CAB1323)
- SKU:
- CAB1323
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MDP1
- MIRAS
- MTDPS4A
- MTDPS4B
- PEO
- POLG1
- POLGA
- SANDO
- SCAE
Frequently bought together:
Description
Product Name: | DNA Polymerase gamma Rabbit Monoclonal Antibody |
SKU: | CAB1323 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1140-1239 of human DNA Polymerase gamma (P54098). |
Sequence: | LVRE EDRY RAAL ALQI TNLL TRCM FAYK LGLN DLPQ SVAF FSAV DIDR CLRK EVTM DCKT PSNP TGME RRYG IPQG EALD IYQI IELT KGSL EKRS QPGP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B; DNA Polymerase gamma |
Positive Sample: | HT-29,293T,Mouse testis,Mouse brain,Rat liver,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Mitochondrion matrix, mitochondrion nucleoid. |
Calculated MW: | 140kDa |
Observed MW: | 140kDa |
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5428 |
Clone Number: | ARC1871 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |