DMAP1 Rabbit Monoclonal Antibody (CAB19281)
- SKU:
- CAB19281
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DMAP1
- DNMAP1
- DNMTAP1
- EAF2
- MEAF2
- SWC4
- DNA methyltransferase 1-associated protein 1
- Research Area:
- Developmental Biology
Description
Product Name: | DMAP1 Rabbit Monoclonal Antibody |
SKU: | CAB19281 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 368-467 of human DMAP1 (Q9NPF5). |
Sequence: | RSDL VLLY ELKQ ACAN CEYE LQML RHRH EALA RAGV LGGP ATPA SGPG PASA EPAV TEPG LGPD PKDT IIDV VGAP LTPN SRKR RESA SSSS SVKK AKKP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | EAF2; SWC4; MEAF2; DNMAP1; DNMTAP1; DMAP1 |
Positive Sample: | HeLa,PC-12,HepG2 |
Conjugate: | Unmodified |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | 60kDa |
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Purification Method: | Affinity purification |
Gene ID: | 55929 |
Clone Number: | ARC2462 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |