The Anti-DDX55 Polyclonal Antibody (CAB20170) is a valuable tool for researchers studying DDX55, a protein involved in RNA processing and gene expression regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DDX55 protein, this antibody enables precise detection and analysis in various cell types, making it an essential reagent for studies in molecular biology, RNA biology, and cancer research.DDX55 is a key player in RNA metabolism, functioning as an RNA helicase that unwinds RNA secondary structures and facilitates various cellular processes such as transcription and translation.
Its role in gene regulation and RNA processing implicates DDX55 in diseases like cancer, where abnormal RNA metabolism can drive tumorigenesis. Targeting DDX55 for further research may provide insights into its potential as a therapeutic target in cancer treatment or other RNA-related disorders. Understanding the molecular mechanisms of DDX55 is essential for unraveling its functions and potential implications in disease pathology.
Product Name:
DDX55 Rabbit Polyclonal Antibody
SKU:
CAB20170
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human DDX55 (NP_065987.1).
This gene encodes a member of protein family containing a characteristic Asp-Glu-Ala-Asp (DEAD) motif. These proteins are putative RNA helicases, and may be involved in a range of nuclear processes including translational initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Multiple alternatively spliced transcript variants have been found for this gene. Pseudogenes have been identified on chromosomes 1 and 12.
Purification Method:
Affinity purification
Gene ID:
57696
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX55 Rabbit pAb (CAB20170) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
