The DDR1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0306) is a powerful tool for research involving the DDR1 protein, a receptor tyrosine kinase involved in cell adhesion and migration. This antibody, produced through innovative chimeric recombinant technology, offers high specificity and sensitivity in detecting DDR1 in human samples. Validated for use in Western blot applications, it enables precise analysis of DDR1 expression levels in various cell types.DDR1, also known as discoidin domain receptor 1, plays a crucial role in cell signaling pathways that regulate processes like cell growth, differentiation, and matrix remodeling. Its involvement in these fundamental biological processes makes DDR1 a valuable target for research in fields such as cancer biology, fibrosis, and tissue regeneration.
Understanding the function of DDR1 is essential for developing targeted therapies that can modulate its activity in disease contexts.Overall, the DDR1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0306) offers researchers a valuable tool for investigating the role of DDR1 in cellular processes and disease pathology. Its high specificity and reliability make it an ideal choice for studies aiming to elucidate the molecular mechanisms underlying DDR1-mediated signaling pathways.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
