The DCTN5 Polyclonal Antibody (CAB19251) is a valuable tool for research involving DCTN5, a protein involved in cytoplasmic dynein function. The antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It specifically binds to the DCTN5 protein, allowing for precise detection and analysis in various cell types.DCTN5 is a component of the dynactin complex, which is essential for the retrograde transport of organelles and vesicles along microtubules.
Dysregulation of DCTN5 has been linked to various disorders, making it a target of interest for research in cell biology and neurodegenerative diseases.By using the DCTN5 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of DCTN5, ultimately leading to a better understanding of its role in cellular processes and disease pathology. Its high specificity and sensitivity make it an ideal tool for studies in molecular biology and neuroscience.
Product Name:
DCTN5 Rabbit Monoclonal Antibody
SKU:
CAB19251
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-182 of human DCTN5 (Q9BTE1).
This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
84516
Clone Number:
ARC2412
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various lysates, using DCTN5 antibody (CAB19251) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
