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DARPP32 Rabbit Monoclonal Antibody (CAB4027)

SKU:
CAB4027
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
DARPP-32
DARPP32
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:DARPP32 Rabbit Monoclonal Antibody
SKU:CAB4027
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DARPP32 (Q9UD71).
Sequence:MDPK DRKK IQFS VPAP PSQL DPRQ VEMI RRRR PTPA MLFR LSEH SSPE EEAS PHQR ASGE GHHL KSKR PNPC AYTP PSLK AVQR IAES HLQS ISNL NENQ
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:DARPP32; DARPP-32
Positive Sample:Mouse brain, Rat brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytosol, nucleus
Calculated MW:23kDa
Observed MW:32kDa

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:84152
Clone Number:ARC2095
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using DARPP32 Rabbit mAb (CAB4027) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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