The DAB2IP Polyclonal Antibody (CAB20493) is a valuable tool for researchers studying DAB2IP, a protein involved in controlling cell growth and survival pathways. This antibody, produced in rabbits, has a high affinity for human samples and has been validated for use in Western blot applications. By specifically binding to the DAB2IP protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in cancer biology and signal transduction pathways.DAB2IP, also known as DOC-2/DAB2 Interactive Protein, is a tumor suppressor that regulates cell proliferation and survival through multiple molecular mechanisms.
Dysregulation of DAB2IP has been implicated in various cancers and is associated with poor prognosis in patients. Research on DAB2IP is essential for understanding its role in tumorigenesis and developing targeted therapies for cancer treatment.By utilizing the DAB2IP Polyclonal Antibody (CAB20493), researchers can gain insights into the function and regulation of DAB2IP in cancer cells, providing valuable information for the development of novel therapeutic strategies. This antibody is a valuable resource for studies aiming to unravel the complex mechanisms underlying cancer progression and metastasis.
Product Name:
DAB2IP Rabbit Polyclonal Antibody
SKU:
CAB20493
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 205-320 of human DAB2IP (NP_619723.1).
DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).
Purification Method:
Affinity purification
Gene ID:
153090
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of PC-12 cells using DAB2IP Rabbit pAb (CAB20493) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
