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Cytokeratin 4 (KRT4) Rabbit Monoclonal Antibody (CAB0013)

SKU:
CAB0013
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CK-4
CK4
CYK4
K4
WSN1
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Cytokeratin 4 (KRT4) Rabbit Monoclonal Antibody
SKU:CAB0013
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 4 (KRT4) (P19013).
Sequence:MIAR QQCV RGGP RGFS CGSA IVGG GKRG AFSS VSMS GGAG RCSS GGFG SRSL YNLR GNKS ISMS VAGS RQGA CFGG AGGF GTGG FGGG FGGS FSGK GGPG
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:K4; CK4; CK-4; CYK4; WSN1; Cytokeratin 4 (KRT4)
Positive Sample:A549,A-431,Mouse stomach
Conjugate:Unconjugated
Cellular Localization:cell surface, cytosol, intermediate filament cytoskeleton, nucleus
Calculated MW:56kDa
Observed MW:57kDa

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Purification Method:Affinity purification
Gene ID:3851
Clone Number:ARC1804
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Cytokeratin 4 (KRT4) (KRT4) Rabbit mAb (CAB0013) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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