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Cytokeratin 2e Rabbit Monoclonal Antibody (CAB2615)

SKU:
CAB2615
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CK-2e
K2e
KRT2A
KRT2E
KRTE
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Cytokeratin 2e Rabbit Monoclonal Antibody
SKU:CAB2615
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 293-422 of humanKRT2(P35908).
Sequence:YMIK VELQ SKVD LLNQ EIEF LKVL YDAE ISQI HQSV TDTN VILS MDNS RNLD LDSI IAEV KAQY EEIA QRSK EEAE ALYH SKYE ELQV TVGR HGDS LKEI KIEI SELN RVIQ RLQG EIAH VKKQ CKNV QD
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:K2e; KRTE; CK-2e; KRT2A; KRT2E; Cytokeratin 2e (KRT2)
Positive Sample:A-431
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol, extracellular exosome, extracellular space, nucleus
Calculated MW:65kDa
Observed MW:65kDa

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Purification Method:Affinity purification
Gene ID:3849
Clone Number:ARC1925
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from A-431 cells, using Cytokeratin 2e (KRT2) Rabbit mAb (CAB2615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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