Cytokeratin 2e Rabbit Monoclonal Antibody (CAB2615)
The Anti-Cytokeratin 2E (KRT2) Antibody (CAB2615) is a valuable tool for research involving cytokeratin 2E, a protein found in epithelial cells that plays a role in maintaining cell structure and integrity. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including immunohistochemistry and Western blotting.Cytokeratin 2E is a marker for epithelial differentiation and is commonly used in studies related to skin diseases, cancer, and tissue regeneration. The Anti-Cytokeratin 2E Antibody binds specifically to this protein, allowing for accurate detection and analysis in a range of cell types and tissue samples.
Its high specificity and sensitivity make it an essential tool for researchers in the fields of dermatology, oncology, and cell biology.Investigating the expression and function of cytokeratin 2E can provide valuable insights into the pathogenesis of various diseases and conditions, as well as potential therapeutic targets. This antibody enables researchers to explore the role of cytokeratin 2E in normal tissue development and homeostasis, as well as its potential involvement in disease progression and treatment responses.
Product Name:
Cytokeratin 2e Rabbit Monoclonal Antibody
SKU:
CAB2615
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 293-422 of humanKRT2(P35908).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Purification Method:
Affinity purification
Gene ID:
3849
Clone Number:
ARC1925
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from A-431 cells, using Cytokeratin 2e (KRT2) Rabbit mAb (CAB2615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
