The Anti-Cytokeratin 18 (KRT18) Antibody (CAB19778) is a valuable tool for researchers studying cytokeratin 18, a protein involved in maintaining the structural integrity of epithelial cells. This antibody, developed using cutting-edge technology, specifically targets KRT18 in human samples and is validated for use in various applications including immunohistochemistry and immunofluorescence.Cytokeratin 18 is widely used as a biomarker in cancer research, particularly in the diagnosis and prognosis of various types of tumors. By utilizing this antibody, researchers can accurately detect and analyze KRT18 expression in different cell types, providing crucial insights into the pathogenesis of cancer and other diseases involving epithelial cells.
Furthermore, the Anti-Cytokeratin 18 (KRT18) Antibody (CAB19778) offers high specificity and sensitivity, making it a reliable tool for studies in cell biology, oncology, and pathology. Its ability to selectively bind to KRT18 makes it an essential component for understanding the role of this protein in normal cell function and disease progression.
Product Name:
Cytokeratin 18 (KRT18) Rabbit Monoclonal Antibody
SKU:
CAB19778
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-430 of human Cytokeratin 18 (KRT18) (P05783).
adherens junction, cytoplasm, cytoskeleton, cytosol, extracellular exosome, microtubule organizing center, nuclear matrix, nucleolus, perinuclear region of cytoplasm
Calculated MW:
48kDa
Observed MW:
48kDa
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3875
Clone Number:
ARC2303
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cytokeratin 18 (KRT18) Rabbit mAb (CAB19778) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
