The Cytochrome P450 4A11 Polyclonal Antibody (CAB19662) is a vital tool for researchers studying the role of CYP4A11, an enzyme belonging to the cytochrome P450 family involved in the metabolism of endogenous and exogenous compounds. This antibody, produced through rabbit immunization, displays high reactivity towards human samples and has been validated for Western blot applications.CYP4A11 is known for its involvement in the metabolism of fatty acids, steroids, and eicosanoids, making it a key player in lipid homeostasis and inflammation regulation. Its dysregulation has been linked to various diseases, including cardiovascular disorders, diabetes, and cancer.
By binding specifically to the CYP4A11 protein, this antibody enables researchers to investigate the expression and activity of the enzyme in different cell types, providing valuable insights for studies in pharmacology and toxicology.Unraveling the functions of CYP4A11 is essential for advancing our understanding of drug metabolism, lipid signaling, and the pathogenesis of related diseases. The availability of a reliable antibody like CAB19662 facilitates research efforts aimed at developing new therapeutic strategies and improving drug efficacy and safety.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1579
Clone Number:
ARC2219
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cytochrome P450 4A (CYP4A11) (CYP4A11) Rabbit mAb (CAB19662) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
