CYB5R3 Monoclonal Antibody (CAB20892)
- SKU:
- CAB20892
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Plant
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
Product Name: | CYB5R3 Monoclonal Antibody |
SKU: | CAB20892 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CYB5R3 (P00387). |
Sequence: | MGAQ LSTL GHMV LFPV WFLY SLLM KLFQ RSTP AITL ESPD IKYP LRLI DREI ISHD TRRF RFAL PSPQ HILG LPVG QHIY LSAR IDGN LVVR PYTP ISSD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | B5R; DIA1; CYB5R3 |
Positive Sample: | Hep G2, A-431, K-562, Rat liver, Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Lipid-anchor, Mitochondrion outer membrane. |
Calculated MW: | 34kDa |
Observed MW: | 35kDa |
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
Purification Method: | Affinity purification |
Gene ID: | 1727 |
Clone Number: | ARC2849 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |