The Anti-CXCR7 Antibody (CAB8991) is a valuable tool for researchers studying CXCR7, a chemokine receptor involved in various biological processes such as cell migration, angiogenesis, and immune response modulation. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the CXCR7 protein, this antibody enables reliable detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology, oncology, and vascular biology.
CXCR7 is known to play a crucial role in tumor growth, metastasis, and inflammation, making it a potential target for therapeutic intervention in cancer and inflammatory diseases. By understanding the function and regulation of CXCR7, researchers can explore new avenues for developing targeted therapies that modulate immune responses and inhibit pathological processes. The Anti-CXCR7 Antibody (CAB8991) is a valuable tool for investigating the role of CXCR7 in health and disease, paving the way for novel treatment strategies in oncology and immunology.
Product Name:
CXCR7 Rabbit Monoclonal Antibody
SKU:
CAB8991
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 263-362 of human CXCR7 (NP_064707.1).
Cell surface, Early endosome, Nucleus, Plasma membrane, Recycling endosome
Calculated MW:
41kDa
Observed MW:
38kDa
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
Purification Method:
Affinity purification
Gene ID:
57007
Clone Number:
ARC1374
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CXCR7 antibody (CAB8991) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
