The Anti-CXCR5 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0327) is a cutting-edge tool for research in the field of immunology. This antibody targets CXCR5, a chemokine receptor known to play a key role in the migration of B cells to lymphoid organs. Produced in rabbits, this antibody is highly specific and sensitive for detecting CXCR5 in human samples. It has been validated for use in Western blot applications, allowing for precise and accurate analysis of CXCR5 expression in various cell types.CXCR5 is involved in the regulation of immune responses, particularly in the context of B cell trafficking and the formation of germinal centers.
Studies have shown that dysregulation of CXCR5 can lead to abnormalities in immune function, making it a potential target for therapeutic interventions in conditions such as autoimmune diseases and lymphoid malignancies.By using this Anti-CXCR5 Chimeric Recombinant Rabbit Monoclonal Antibody, researchers can gain valuable insights into the role of CXCR5 in immune modulation and lymphocyte homing, paving the way for the development of novel treatments and therapies in the field of immunology.
SKU:
HDAB0327
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC679
Synonyms:
Blr1; CXC-R5; CXCR-5; Gpcr6; MDR15
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes.[UniProtKB/Swiss-Prot Function]
