The Anti-CXCR4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0328) is a cutting-edge tool for researchers studying CXCR4, a critical chemokine receptor involved in various biological processes, such as cell migration, hematopoiesis, and immune responses. This high-quality antibody, developed using innovative technology, offers superior sensitivity and specificity in detecting CXCR4 in human samples, making it ideal for applications like immunohistochemistry and flow cytometry.CXCR4, also known as C-X-C chemokine receptor type 4, plays a key role in cancer metastasis, HIV infection, and inflammatory diseases, making it a promising target for therapeutic intervention.
By targeting CXCR4, researchers can gain valuable insights into disease mechanisms and potential treatment strategies. The Anti-CXCR4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0328) enables precise visualization and quantification of CXCR4 expression in cells and tissues, facilitating detailed molecular analysis and functional studies in the fields of oncology, virology, and immunology.
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
