The CTR1 (SLC31A1) Polyclonal Antibody (CAB0773) is a valuable tool for researchers studying the copper transport protein 1 (CTR1), which plays a crucial role in copper uptake and distribution in cells. This highly reactive antibody, raised in rabbits, has been validated for use in Western blot applications and is specific for human samples.CTR1 is essential for maintaining copper homeostasis and for regulating copper-dependent processes in the body. Dysregulation of copper transport has been linked to various diseases, including copper deficiency syndromes, Wilson's disease, and certain types of cancer.
By targeting CTR1 with this antibody, researchers can study its expression levels and localization in different cell types, shedding light on its role in health and disease.The CTR1 Polyclonal Antibody (CAB0773) is a valuable tool for investigations into the molecular mechanisms underlying copper metabolism and its impact on cellular function. Its specificity and sensitivity make it an ideal choice for studies in biochemistry, cell biology, and therapeutic development targeting copper dysregulation-related disorders.
Product Name:
CTR1/SLC31A1 Rabbit Monoclonal Antibody
SKU:
CAB0773
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CTR1/SLC31A1 (NP_001850.1).
The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper.
Purification Method:
Affinity purification
Gene ID:
1317
Clone Number:
ARC2537
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTR1/SLC31A1 Rabbit mAb (CAB0773) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
