The CTIP2/BCL11B Polyclonal Antibody (CAB20483) is a valuable tool for researchers studying the role of CTIP2/BCL11B in gene regulation and cellular development. This antibody, produced in rabbits, is highly specific and reacts with human samples, making it ideal for use in Western blot and immunohistochemistry applications.CTIP2/BCL11B is a transcription factor that plays a critical role in various cellular processes, including hematopoiesis, neuronal development, and immune regulation. Dysregulation of CTIP2/BCL11B has been linked to the development of various cancers, neurological disorders, and immune-related diseases.
Therefore, studying the expression and activity of CTIP2/BCL11B is essential for understanding its function in health and disease.By using the CTIP2/BCL11B Polyclonal Antibody, researchers can accurately detect and analyze CTIP2/BCL11B expression in different cell types and tissues, leading to a better understanding of its role in molecular pathways and potential therapeutic targets. This antibody is a valuable tool for advancing research in fields such as oncology, neurobiology, and immunology.
Product Name:
CTIP2/BCL11B Rabbit Polyclonal Antibody
SKU:
CAB20483
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-310 of human CTIP2/BCL11B (NP_612808.1).
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
64919
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTIP2/BCL11B Rabbit pAb (CAB20483) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
