The Anti-CRMP5/DPYSL5 Antibody (CAB3503) is a high-quality polyclonal antibody designed for research involving CRMP5/DPYSL5, a protein implicated in various cellular processes including neuronal development and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CRMP5/DPYSL5, also known as collapsin response mediator protein 5, is involved in neuronal differentiation and axonal guidance. Dysregulation of CRMP5/DPYSL5 has been linked to neurological disorders such as Alzheimer's disease and multiple sclerosis, highlighting its importance in the nervous system.
Research on CRMP5/DPYSL5 could provide insights into these conditions and aid in the development of potential therapeutic strategies.This antibody binds specifically to the CRMP5/DPYSL5 protein, allowing for its detection and analysis in various cell types. Its versatility makes it ideal for studies in neuroscience, neurology, and neurodegenerative diseases. Understanding the function and regulation of CRMP5/DPYSL5 could lead to advancements in the treatment of neurological disorders and contribute to our knowledge of the brain's intricate mechanisms.
Product Name:
CRMP5/DPYSL5 Rabbit Monoclonal Antibody
SKU:
CAB3503
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 465-564 of human CRMP5/DPYSL5 (Q9BPU6).
This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
56896
Clone Number:
ARC2020
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CRMP5/DPYSL5 Rabbit mAb (CAB3503) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
