The CRMP1 Polyclonal Antibody (CAB2390) is a valuable tool for researchers studying CRMP1, a protein involved in neuronal development and function. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples, making it ideal for various research applications, including Western blotting.CRMP1, also known as collapsin response mediator protein 1, is crucial for axon guidance and neuronal differentiation, making it a key player in nervous system development. Dysregulation of CRMP1 has been linked to neurological disorders such as Alzheimer's disease and schizophrenia, highlighting the importance of studying this protein in the context of neurobiology.
By enabling precise detection and analysis of CRMP1 in different cell types, the CAB2390 antibody allows researchers to further understand the role of CRMP1 in neuronal processes and its potential implications in disease pathology. This antibody is a valuable tool for advancing research in neurobiology and exploring potential therapeutic strategies for neurodegenerative disorders.
Product Name:
CRMP1 Rabbit Monoclonal Antibody
SKU:
CAB2390
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human CRMP1 (Q14194).
Cytoplasm, Centrosome, Cytoskeleton, Microtubule organizing center, Spindle.
Calculated MW:
62kDa
Observed MW:
62kDa
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1400
Clone Number:
ARC1918
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CRMP1 Rabbit mAb (CAB2390) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
