The Anti-CRABP1 Antibody (CAB5434) is a highly specific tool for researchers studying cellular retinoic acid binding protein 1 (CRABP1), a protein involved in the regulation of retinoic acid signaling pathways. This antibody, produced in rabbits, has been validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.CRABP1 is known to play a crucial role in cellular differentiation, proliferation, and apoptosis, making it a key player in developmental processes and cancer progression. By targeting CRABP1 with this antibody, researchers can gain valuable insights into the function and regulation of this protein in both normal and diseased states, paving the way for potential therapeutic interventions in cancer and other diseases affected by dysregulated retinoic acid signaling pathways.
Overall, the Anti-CRABP1 Antibody (CAB5434) is a valuable tool for investigators looking to dissect the role of CRABP1 in various biological processes and diseases, ultimately contributing to the advancement of biomedical research and the development of novel therapeutic strategies.
Product Name:
CRABP1 Rabbit Monoclonal Antibody
SKU:
CAB5434
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 58-137 of human CRABP1 (P29762).
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue.
Purification Method:
Affinity purification
Gene ID:
1381
Clone Number:
ARC1991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CRABP1 Rabbit mAb (CAB5434) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
