The Anti-CR2 (CD21) Antibody (CAB1267) offered by Assay Genie is a valuable tool for researchers studying the CD21 protein, a cell surface receptor that plays a crucial role in immune responses. This polyclonal antibody, generated in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blotting.CD21, also known as complement receptor 2 (CR2), is involved in the regulation of B cell activation and immune responses. It serves as a receptor for complement component C3d, which facilitates antigen presentation and enhances the immune response. By targeting CD21 with this antibody, researchers can study its expression and function in different cell types, providing insights into its role in immunology and potential implications in conditions such as autoimmune diseases and infections.
Understanding the function of CD21 is essential for unraveling its potential as a therapeutic target and developing strategies to modulate immune responses in various disease contexts. By using the Anti-CR2 (CD21) Antibody (CAB1267), researchers can delve deeper into the mechanisms underlying immune regulation and explore new avenues for treatment development.
Product Name:
CD21 Rabbit Monoclonal Antibody
SKU:
CAB1267
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 934-1033 of human CR2/CD21 (P20023).
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1380
Clone Number:
ARC1868
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Jurkat cells, using CR2/CD21 Rabbit mAb (CAB1267) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
