The CPSF73 Polyclonal Antibody (CAB2222) is a valuable tool for researchers studying CPSF73, a key protein involved in pre-mRNA 3' end processing. This antibody, produced in rabbits, is highly specific to human CPSF73 and has been validated for use in Western blot applications. By binding to CPSF73, this antibody allows for precise detection and analysis of the protein in various cell types, making it an essential component in studies related to gene expression regulation and RNA processing.CPSF73 is a crucial component of the cleavage and polyadenylation complex, playing a vital role in mRNA maturation. Dysregulation of CPSF73 expression or activity has been linked to various diseases, including cancer and neurological disorders.
By investigating the function of CPSF73, researchers can gain insights into the underlying mechanisms of these conditions and explore novel therapeutic strategies targeting RNA processing pathways.Overall, the CPSF73 Polyclonal Antibody (CAB2222) is a valuable tool for researchers seeking to unravel the intricate mechanisms of pre-mRNA processing and its implications in human health and disease. Its high specificity and reliability make it an ideal choice for studies in molecular biology, genetics, and biochemistry.
Product Name:
CPSF73 Rabbit Monoclonal Antibody
SKU:
CAB2222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 585-684 of human CPSF3 (Q9UKF6).
This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the cleavage and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-cleavage site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing.
Purification Method:
Affinity purification
Gene ID:
51692
Clone Number:
ARC2567
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CPSF73 antibody (CAB2222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
