Cox2 Rabbit Monoclonal Antibody (CAB3560)
- SKU:
- CAB3560
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- COX-2
- COX2
- GRIPGHS
- PGG/HS
- PGHS-2
- PHS-2
- hCox-2
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Cox2 Rabbit Monoclonal Antibody |
SKU: | CAB3560 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 505-604 of human COX2/PTGS2 (P35354). |
Sequence: | GETM VEVG APFS LKGL MGNV ICSP AYWK PSTF GGEV GFQI INTA SIQS LICN NVKG CPFT SFSV PDPE LIKT VTIN ASSS RSGL DDIN PTVL LKER STEL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS; COX2/PTGS2 |
Positive Sample: | HeLa+LPS,RAW 264.7+LPS,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | caveola, cytoplasm, endoplasmic reticulum, endoplasmic reticulum lumen, neuron projection |
Calculated MW: | 69kDa |
Observed MW: | 72kDa |
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Purification Method: | Affinity purification |
Gene ID: | 5743 |
Clone Number: | ARC0800 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% sodium azide,0.05% BSA,50% glycerol,pH7.3. |