The Anti-Complement Factor H Antibody (CAB8798) is a high-quality monoclonal antibody designed for research involving complement factor H, a key regulatory protein in the complement system. This antibody, produced in mice, is specifically reactive with human samples and has been validated for use in various immunoassays such as Western blot and ELISA.Complement factor H is a critical player in the regulation of the complement system, which is a major component of the immune response. Dysregulation of complement factor H is associated with various diseases, including autoimmune disorders and inflammatory conditions.
By targeting complement factor H, researchers can gain insights into the underlying mechanisms of these diseases and potentially develop novel therapeutic strategies.This antibody binds specifically to complement factor H, allowing for accurate detection and analysis in a variety of experimental settings. Its high specificity and sensitivity make it an essential tool for studies in immunology, inflammation, and disease pathology. Researchers interested in investigating the role of complement factor H in health and disease can rely on this antibody for reliable and reproducible results.
Product Name:
Factor H Rabbit Monoclonal Antibody
SKU:
CAB8798
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Complement factor H (P08603).
blood microparticle, extracellular exosome, extracellular region, extracellular space
Calculated MW:
139kDa
Observed MW:
160kDa
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
3075
Clone Number:
ARC1306
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of BxPC-3 cells, using Complement factor H antibody (CAB8798) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
