Collagen III alpha 1/COL3A1 Rabbit Monoclonal Antibody (CAB0817)
The Anti-Collagen III Alpha 1 (COL3A1) Polyclonal Antibody (CAB0817) is a powerful tool for researchers studying collagen III, a key component of the extracellular matrix. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the COL3A1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential asset for investigations in areas such as tissue remodeling, wound healing, and fibrosis.Collagen III is essential for the structural integrity of tissues and organs, playing a crucial role in maintaining skin elasticity, blood vessel strength, and connective tissue function. Dysregulation of collagen III synthesis and organization is associated with various pathological conditions, including fibrotic diseases, cardiovascular disorders, and skin aging.
As such, understanding the mechanisms governing collagen III expression and function is vital for developing therapies aimed at preventing or treating these conditions.The Anti-Collagen III Alpha 1 (COL3A1) Polyclonal Antibody (CAB0817) offers researchers a reliable tool for investigating the role of collagen III in health and disease. Its high specificity, sensitivity, and reproducibility make it a valuable asset for studies in fields such as tissue biology, regenerative medicine, and therapeutic development. By utilizing this antibody, researchers can gain insights into the complex biology of collagen III and its implications for various medical conditions,
Product Name:
Collagen III alpha 1/COL3A1 Rabbit Monoclonal Antibody
SKU:
CAB0817
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human Collagen III alpha 1/COL3A1 (P02461).
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome type IV, and with aortic and arterial aneurysms.
Purification Method:
Affinity purification
Gene ID:
1281
Clone Number:
ARC2542
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Collagen III alpha 1/COL3A1 Rabbit mAb (CAB0817) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
