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COL2A1 Rabbit Polyclonal Antibody (CAB19308)

SKU:
CAB19308
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
COL2A1
ANFH
AOM
COL11A3
SEDC
STL1
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:COL2A1 Rabbit Polyclonal Antibody
SKU:CAB19308
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1200-1300 of human COL2A1 (NP_001835.3).
Sequence:GPPG NPGP PGPP GPPG PGID MSAF AGLG PREK GPDP LQYM RADQ AAGG LRQH DAEV DATL KSLN NQIE SIRS PEGS RKNP ARTC RDLK LCHP EWKS GDYW I
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:100 - 1:500 IF/ICC,1:50 - 1:200
Synonyms:AOM; ANFH; SEDC; STL1; COL11A3; COL2A1
Positive Sample:Mouse skeletal muscle
Conjugate:Unconjugated
Cellular Localization:Secreted, extracellular matrix, extracellular space.
Calculated MW:142kDa
Observed MW:141kDa

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.

Purification Method:Affinity purification
Gene ID:1280
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Mouse skeletal muscle, using COL2A1 Rabbit pAb (CAB19308) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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