The COL16A1 Polyclonal Antibody (CAB18837) is a valuable tool for researchers studying COL16A1, a key component of the extracellular matrix that plays a critical role in tissue development and maintenance. This antibody, produced in rabbits, has a high affinity for human samples and has been validated for use in Western blot applications. By binding specifically to the COL16A1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential tool for research in fields such as cell biology, tissue engineering, and regenerative medicine.COL16A1, a collagen protein with an important role in the structural integrity of tissues, is involved in processes such as cell adhesion, migration, and differentiation.
Dysregulation of COL16A1 expression has been linked to various diseases, including fibrosis, cancer, and connective tissue disorders. By studying the function of COL16A1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for treatment.Overall, the COL16A1 Polyclonal Antibody is a valuable resource for scientists conducting research on extracellular matrix proteins and their roles in tissue function and disease. Its specificity and reliability make it a versatile tool for a wide range of experimental applications, helping to advance our understanding of COL16A1 and its implications for human health.
Product Name:
COL16A1 Rabbit Polyclonal Antibody
SKU:
CAB18837
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human COL16A1 (NP_001847.3).
endoplasmic reticulum lumen, extracellular region, extracellular space
Calculated MW:
158kDa
Observed MW:
145kDa
This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion.
Purification Method:
Affinity purification
Gene ID:
1307
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from PC-3 cells, using COL16A1 Rabbit pAb (CAB18837) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
