The CNN3 Polyclonal Antibody (CAB20352) is a valuable tool for researchers studying CNN3, a cell surface protein that plays a role in various cellular functions, including actin cytoskeleton organization and cell migration. This antibody, produced in rabbits, is highly specific for CNN3 in human samples and is validated for use in Western blot applications. By targeting the CNN3 protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for studies in cell biology, cancer research, and beyond.CNN3, also known as calponin 3, is involved in regulating actin dynamics and cell motility, making it a key player in processes such as cell adhesion and migration.
Its functions extend to roles in smooth muscle contraction and muscle cell differentiation, highlighting its importance in various physiological processes. Researchers studying CNN3 can gain valuable insights into its functions and potential implications in diseases such as cancer, cardiovascular disorders, and muscle-related conditions. By understanding the mechanisms and interactions involving CNN3, researchers can contribute to the development of potential therapeutics targeting this protein in various disease contexts.
Product Name:
CNN3 Rabbit Polyclonal Antibody
SKU:
CAB20352
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-329 of human CNN3 (NP_001830.1).
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction.
Purification Method:
Affinity purification
Gene ID:
1266
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CNN3 antibody (CAB20352) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
