CLPX Monoclonal Antibody (CAB20871)
- SKU:
- CAB20871
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Product Name: | CLPX Monoclonal Antibody |
| SKU: | CAB20871 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 534-633 of human CLPX (O76031). |
| Sequence: | SMDK CELN VTED ALKA IARL ALER KTGA RGLR SIME KLLL EPMF EVPN SDIV CVEV DKEV VEGK KEPG YIRA PTKE SSEE EYDS GVEE EGWP RQAD AANS |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:100 - 1:500 |
| Synonyms: | EPP2; CLPX |
| Positive Sample: | HepG2,U-937,HeLa,Mouse liver,Rat liver |
| Conjugate: | Unconjugated |
| Cellular Localization: | cytosol, mitochondrial endopeptidase Clp complex, mitochondrial inner membrane, mitochondrial matrix, mitochondrial nucleoid, mitochondrion, nucleoplasm |
| Calculated MW: | 69kDa |
| Observed MW: | 69kDa |
The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit encoded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 10845 |
| Clone Number: | ARC2812 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of extracts of various cell lines, using CLPX antibody (CAB20871) at1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s. |
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