The CLPP Polyclonal Antibody (CAB3214) is a valuable tool for researchers studying the Clp protease proteolytic subunit, an essential component of the mitochondrial ATP-dependent protease. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CLPP protein, this antibody allows for the detection and analysis of CLPP in various cell types, making it ideal for studies in mitochondrial function, protein degradation, and cellular stress response research.The CLPP protein is crucial for maintaining mitochondrial homeostasis and proper cellular function, playing a key role in protein quality control and mitochondrial biogenesis.
Dysregulation of CLPP has been implicated in various diseases, including neurodegenerative disorders, metabolic syndromes, and mitochondrial dysfunction-related conditions. Therefore, understanding the function and regulation of CLPP is essential for developing targeted therapies and interventions for these health challenges.Overall, the CLPP Polyclonal Antibody (CAB3214) offers researchers a reliable and specific tool for investigating the role of CLPP in cellular processes and disease pathogenesis, ultimately advancing our understanding of mitochondrial biology and potential therapeutic strategies.
Product Name:
CLPP Rabbit Monoclonal Antibody
SKU:
CAB3214
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 178-277 of human CLPP (Q16740).
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.
Purification Method:
Affinity purification
Gene ID:
8192
Clone Number:
ARC1929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CLPP Rabbit mAb (CAB3214) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
