The CLEC9A Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0295) is a cutting-edge research tool designed for the study of CLEC9A, a cell surface receptor involved in antigen uptake and dendritic cell activation. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been rigorously validated for use in various applications including immunofluorescence and flow cytometry.CLEC9A, also known as DNGR-1, plays a crucial role in immune responses by facilitating the uptake and processing of antigens for presentation to T cells. Its involvement in dendritic cell function highlights its importance in shaping immune responses and potentially influencing antitumor immunity.
By targeting CLEC9A, researchers can gain valuable insights into the mechanisms underlying immune activation and regulation, providing valuable information for the development of novel immunotherapies and vaccines.Overall, the CLEC9A Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0295) serves as a powerful tool for investigating the functions of CLEC9A in various research contexts, including immunology, cancer biology, and vaccine development. Its high specificity and sensitivity make it a valuable asset for scientists seeking to unravel the complexities of immune activation and modulation.
SKU:
HDAB0295
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC469
Synonyms:
CD370, DNGR-1, DNGR1, UNQ9341
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
