The Anti-CIRBP Antibody (CAB19290) is developed for research purposes involving Cirbp, a cold-inducible RNA-binding protein involved in various cellular processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the Cirbp protein, it enables accurate detection and analysis in different cell types, making it ideal for studies in molecular biology and cellular physiology.
Cirbp is known to play a critical role in response to environmental stressors, particularly cold temperatures, and has been implicated in processes such as cellular survival, apoptosis, and gene regulation. Its involvement in these pathways makes it a valuable target for research related to conditions like hypothermia, ischemia, and aging. Understanding the functions of Cirbp is essential for exploring its potential therapeutic applications in these contexts.
Product Name:
CIRBP Rabbit Monoclonal Antibody
SKU:
CAB19290
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (Q14011).
Enables mRNA 3'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in mRNA stabilization; positive regulation of translation; and response to UV. Located in cytoplasm and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
1153
Clone Number:
ARC2472
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CIRBP Rabbit mAb (CAB19290) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
