Chromogranin A Rabbit Monoclonal Antibody (CAB9576)
The anti-Chromogranin A Antibody (CAB9576) is a valuable tool for researchers studying Chromogranin A, a protein commonly found in neuroendocrine cells. This polyclonal antibody, generated in rabbits, has high reactivity with human samples and is validated for use in various applications such as immunohistochemistry, immunofluorescence, and ELISA.Chromogranin A is a key marker for neuroendocrine tumors and can be used to diagnose and monitor patients with these types of cancers. By using this antibody, researchers can detect and analyze Chromogranin A expression in tissues and cells, allowing for a better understanding of its role in cancer biology and potential therapeutic targets.
The anti-Chromogranin A Antibody is a valuable tool for researchers in the fields of oncology, endocrinology, and neurobiology. Its specificity and reliability make it an essential component for studies aiming to unravel the complexities of Chromogranin A function and its implications in various diseases.
Product Name:
Chromogranin A Rabbit Monoclonal Antibody
SKU:
CAB9576
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Chromogranin A (P10645).
chromaffin granule, extracellular region, extracellular space, perinuclear region of cytoplasm
Calculated MW:
51kDa
Observed MW:
80kDa
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1113
Clone Number:
ARC1643
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Chromogranin A Rabbit mAb (CAB9576) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
