CHMP2B Rabbit Monoclonal Antibody (CAB19244)
- SKU:
- CAB19244
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CHMP2B
- ALS17
- CHMP2.5
- DMT1
- VPS2-2
- VPS2B
- charged multivesicular body protein 2b
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CHMP2B Rabbit Monoclonal Antibody |
SKU: | CAB19244 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 114-213 of human CHMP2B (Q9UQN3). |
Sequence: | KKMD PQKT LQTM QNFQ KENM KMEM TEEM INDT LDDI FDGS DDEE ESQD IVNQ VLDE IGIE ISGK MAKA PSAA RSLP SAST SKAT ISDE EIER QLKA LGVD |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | DMT1; ALS17; VPS2B; VPS2-2; CHMP2.5; FTDALS7; CHMP2B |
Positive Sample: | HeLa,PC-12,C2C12,RD,SH-SY5Y,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Late endosome membrane, Peripheral membrane protein, Cytosol. |
Calculated MW: | 24kDa |
Observed MW: | 28kDa |
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.
Purification Method: | Affinity purification |
Gene ID: | 25978 |
Clone Number: | ARC2404 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |