CHD3 Rabbit Monoclonal Antibody (CAB6118)
- SKU:
- CAB6118
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- Mi-2a
- Mi2-ALPHA
- ZFH
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | CHD3 Rabbit Monoclonal Antibody |
SKU: | CAB6118 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CHD3 (Q12873). |
Sequence: | MKAA DTVI LWAR SKND QLRI SFPP GLCW GDRM PDKD DIRL LPSA LGVK KRKR GPKK QKEN KPGK PRKR KKRD SEEE FGSE RDEY REKS ESGG SEYG TGPG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ZFH; Mi-2a; SNIBCPS; Mi2-ALPHA; CHD3 |
Positive Sample: | HeLa,Jurkat,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 227kDa |
Observed MW: | 260kDa |
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 1107 |
Clone Number: | ARC1975 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |