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Anti-CEP78 Antibody (CAB20405)

SKU:
CAB20405
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IP63
CRDHL
C9orf81
$167 - $503
Frequently bought together:

Description

Product Name:CEP78 Rabbit pAb
Product Code:CAB20405
Size:50uL, 100uL
Synonyms:IP63, CRDHL, C9orf81
Applications:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant protein of human CEP78.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human
Immunogen:Recombinant protein of human CEP78.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:84131
Observed MW:Refer to figures
Background:This gene encodes a centrosomal protein that is both required for the regulation of centrosome-related events during the cell cycle, and required for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive LRR repeats, and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 to the distal end of the centriole. Naturally occurring mutations in this gene cause defects in primary cilia that result in retinal degeneration and sensorineural hearing loss which are associated with cone-rod degeneration disease as well as Usher syndrome. Low expression of this gene is associated with poor prognosis of colorectal cancer patients.

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