The CEND1 Polyclonal Antibody (CAB5930) is specifically designed for research involving CEND1, a neuronal transcription factor essential for the differentiation and survival of neurons. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications such as Western blot and immunohistochemistry.CEND1, also known as Cell Cycle Exit and Neuronal Differentiation 1, plays a critical role in neuronal development by promoting the exit of neural progenitor cells from the cell cycle and initiating their differentiation into mature neurons.
Dysregulation of CEND1 expression has been linked to neurodevelopmental disorders and neurodegenerative diseases, making it an important focus in neuroscience research.Research utilizing the CEND1 Polyclonal Antibody can provide valuable insights into the mechanisms underlying neuronal differentiation and survival, as well as the potential therapeutic targets for neurological disorders. By enabling the detection and analysis of CEND1 protein in various cell types, this antibody is an essential tool for studies in neurobiology and neurology.
Product Name:
CEND1 Rabbit Monoclonal Antibody
SKU:
CAB5930
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-149 of human CEND1 (NP_057648.2).
The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene.
Purification Method:
Affinity purification
Gene ID:
51286
Clone Number:
ARC2092
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CEND1 Rabbit mAb (CAB5930) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
