The Anti-CEACAM6 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0333) is a powerful tool for researchers studying CEACAM6, a cell adhesion molecule known for its role in cancer progression and metastasis. This antibody, produced from rabbit cells, exhibits high specificity and sensitivity when detecting CEACAM6 in human samples, making it a valuable asset for Western blot and immunohistochemistry applications.CEACAM6, also known as CD66c, is a member of the carcinoembryonic antigen (CEA) family and is overexpressed in various cancer types, including lung, breast, and colon cancer.
Its involvement in tumor cell proliferation, invasion, and angiogenesis makes it a promising target for cancer research and potential therapeutic interventions.By utilizing the Anti-CEACAM6 Chimeric Recombinant Rabbit Monoclonal Antibody, researchers can gain valuable insights into the role of CEACAM6 in cancer development and progression. This antibody's superior performance and specificity make it an indispensable tool for studies aimed at understanding the molecular mechanisms underlying cancer biology and identifying novel therapeutic strategies targeting CEACAM6.
SKU:
HDAB0333
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC685
Synonyms:
CD66c; CEAL; NCA
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
