CEACAM6 Rabbit Monoclonal Antibody (CAB5971)
- SKU:
- CAB5971
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD66c
- CEAL
- NCA
- Research Area:
- Cell Death
Frequently bought together:
Description
| Product Name: | CEACAM6 Rabbit Monoclonal Antibody |
| SKU: | CAB5971 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CEACAM6 (P40199). |
| Sequence: | LTLL SVKR NDAG SYEC EIQN PASA NRSD PVTL NVLY GPDV PTIS PSKA NYRP GENL NLSC HAAS NPPA QYSW FING TFQQ STQE LFIP NITV NNSG SYMC Q |
| Tested Applications: | WB IF/ICC ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
| Synonyms: | NCA; CEAL; CD66c; CEACAM6 |
| Positive Sample: | A-549,Mouse liver |
| Conjugate: | Unconjugated |
| Cellular Localization: | apical plasma membrane, cell surface, extracellular space, plasma membrane |
| Calculated MW: | 37kDa |
| Observed MW: | 37kDa |
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19.
| Purification Method: | Affinity purification |
| Gene ID: | 4680 |
| Clone Number: | ARC2110 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of extracts of various cell lines, using CEACAM6 Rabbit mAb (CAB5971) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s. |
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