The CDX2 Polyclonal Antibody (CAB20222) is a valuable tool for researchers studying CDX2, a transcription factor essential for intestinal development and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications, including immunohistochemistry and Western blotting.CDX2 plays a crucial role in regulating gene expression in the intestinal epithelium, influencing cell proliferation, differentiation, and maintenance of intestinal function.
Dysregulation of CDX2 has been implicated in various gastrointestinal disorders, including colorectal cancer and inflammatory bowel disease.By utilizing the CDX2 Polyclonal Antibody, researchers can accurately detect and analyze CDX2 expression in tissue samples, providing insights into its role in intestinal homeostasis and disease pathogenesis. This antibody is a valuable tool for advancing our understanding of CDX2 biology and its potential as a therapeutic target in gastrointestinal diseases.
Product Name:
CDX2 Rabbit Monoclonal Antibody
SKU:
CAB20222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDX2 (Q99626 ).
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
Purification Method:
Affinity purification
Gene ID:
1045
Clone Number:
ARC3070
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from SW620 cells, using [KD Validated] CDX2 Rabbit mAb (CAB20222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
