The CDX1 Polyclonal Antibody (CAB9546) is a valuable tool for researchers studying the CDX1 transcription factor, which plays a crucial role in regulating gene expression and cell differentiation in the gastrointestinal tract. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards human CDX1 samples, making it ideal for use in applications such as Western blotting.CDX1 is known for its involvement in gut development and maintenance, as well as its potential role in gastrointestinal cancers.
By targeting the CDX1 protein, researchers can gain insight into the molecular mechanisms underlying these processes and potentially identify novel therapeutic targets for related diseases. The CDX1 Polyclonal Antibody is a reliable reagent for exploring the functions of CDX1 in various cellular contexts, advancing our understanding of gastrointestinal biology and pathology.
Product Name:
Cdx1 Rabbit Monoclonal Antibody
SKU:
CAB9546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cdx1 (P47902).
Sequence:
MYVG YVLD KDSP VYPG PARP ASLG LGPQ AYGP PAPP PAPP QYPD FSSY SHVE PAPA PPTA WGAP FPAP KDDW AAAY GPGP AAPA ASPA SLAF GPPP DFSP
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Positive Sample:
HT-29,SGC-7901
Conjugate:
Unconjugated
Cellular Localization:
nucleus
Calculated MW:
28kDa
Observed MW:
28kDa
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.
Purification Method:
Affinity purification
Gene ID:
1044
Clone Number:
ARC1627
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Cdx1 antibody (CAB9546) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
